Predictive factors for decline in postoperative serum AMH levels following endometrioma surgery
Women with endometrioma seek treatment because of symptoms such as pelvic pain and infertility that reduce their quality of life. There are several management approaches including medical and surgical options. Ovarian cystectomy using laparoscopic or robotic devices is one of…
Key Points Lay SummaryAppendiceal Endometriosis Associated With Ovarian and Bladder Endometriosis
There is a significant association between appendiceal, ovarian, and bladder endometriosis, according to a new study published in the scientific journal Archives of Gynecology and Obstetrics. This could be explained by the spread of the disease via the shedding of…
Key Points Lay SummaryPost Surgery Endometrioma Recurrence
Endometrioma is a common form of endometriosis. Endometrioma cystectomy is the preferred treatment, as it is more effective than ablation or laser vaporization in reducing pain and recurrence. While medical treatment can help prevent recurrence after surgery, postoperative hormonal therapy…
Key Points Lay SummaryLow-grade albeit longstanding inflammation may have a pivotal role in the ovary
Academicians from Japan led by Associate Professor Makoto Orisaka published their update related to the role of inflammation in polycystic ovaries, endometriosis, and aging in the medical journal Frontiers in Endocrionology. Inflammation is the response of tissues to noxious stimuli…
Key Points Lay SummaryOvarian endometriomas revisited
Dr. Farr R. Nezhat and his world-renowned team have published their narrative review on ovarian endometrioma in a recent issue of the Obstetrics and Gynecology. Endometriotic cysts (endometriomas) of the ovaries range from small (1–3 cm) to large (20 cm or…
Key Points Lay SummaryLive Birth Rate for ovarian stimulation protocols after laparoscopic endometrioma cystectomy.
The laparoscopic cystectomy of the ovaries is the first-line infertility treatment in patients with endometriomas. However, a possible diminished ovarian capacity after cystectomy with ovarian failure to respond to the gonadotropin stimuli seems an undesirable result of this procedure. Controlled…
Key Points Lay SummaryDiaphragmatic Endometriosis: a Call for Awareness
Dr. Pagano and colleagues from the Department of Gynecology and Obstetrics, University of Bern, Switzerland, have published a prospective cohort study on diaphragmatic involvement in endometriosis patients in a recent issue of “The Journal of Minimally Invasive Gynecology”. Endometriosis is…
Key Points Lay SummaryIron and toxic environmental elements in ovarian endometriomas
It is well-known that the growth of endometriotic lesions is estrogen-dependent and supported by inflammatory processes. In addition to oxidative stress, it is believed that several other factors, including chemicals and environmental factors, and genetic predisposition may play a potential…
Key Points Lay SummaryPostoperative serum markers to predict serum AMH recovery following endometriosis surgery
Women with endometriosis seek treatment including ovarian cystectomy, because of symptoms that reduce their quality of life. Ovarian cystectomy using laparoscopic or robotic devices is the preferred therapy. However, it has been shown in the literature that ovarian reserve is…
Key Points Lay SummaryEndometriotic cyst fluid and the postoperative recurrence of endometriosis
Dr. Xinxin Xu and colleagues from the Department of Obstetrics and Gynecology, School of Medicine, Zhejiang University, China, published their research on the viability of endometrial cells in ovarian cyst fluids in a recent issue of “Journal of Ovarian Research”.…
Key Points Lay SummaryThe Oocyte Quality in Ovarian Endometriosis
Endometrioma is the ovarian involvement of endometriosis affecting up to 44% of women diagnosed with the disease. Owing to the anatomical locus, ovarian endometriosis may impair folliculogenesis and oocyte competence, differing from other forms of endometriosis. When investigating the relationship between…
Key Points Lay SummaryComplex Relation Between Body mass index and endometriosis
This research aimed to find the relationship between BMI and endometriosis especially related to surgical phenotype and lesion location. An observational cohort study was led by Holdsworth-Carson et al, from Australia. The article was recently published in "RBMO" . Many earlier studies report…
Key Points Lay SummaryOvarian, breast and endometrial cancer coexisting with endometriosis.
The invasive nature of endometriosis results in calling the disease " benign cancer". The transformation of endometriosis to malignancy is rare, but when compared to the general population, the relative risk of developing ovarian cancer is 4.2 times greater especially…
Key Points Lay SummaryClinical characteristics linked to recurrence of ovarian endometrioma
Endometriosis affects 10-15% of women. Three types of endometriosis are peritoneal, ovarian, and deep infiltrating endometriosis. Ovarian endometriosis is the most common type of endometriosis with a high rate of recurrence. Laparoscopy is the gold standard treatment for endometriosis and…
Key Points Lay SummaryLong-term Pregnancy Results after Surgical Removal of Endometrioma
Sun et al., from China, investigated the pregnancy outcomes and the related factors in patients with endometrioma and stage III-IV endometriosis along with a long-term follow-up postoperatively. Their study has recently been published in the journal named "Advances in Therapy".…
Key Points Lay SummaryAdiposity, endometriosis type and severity
Dr. Jiyoung from the division of Public Health, Department of Family and Preventive Medicine of the University of Utah, planned a prospective cross-sectional study to assess whether there is an inverse relationship between the adiposity and endometriosis. The results of…
Key Points Lay SummaryFactors affecting risk of ovarian endometriosis malignancy
Getting married when older, having had ovarian endometriosis for longer, giving birth in a shorter time, and other complications in the uterus that are benign may all increase the risk of ovarian endometriosis malignancy. This is according to a study…
Key Points Lay SummaryEndometriosis as an epigenetically regulated disease
Endometriosis is defined as the abnormal growth of endometrial tissue outside of the uterus. It affects about 10% of reproductive age women resulting in severe pain and infertility. Among various theories of endometriosis pathogenesis, not a single one has successfully…
Key Points Lay SummaryDoes ovarian endometriosis affect oocyte quality?
Endometriosis is a very common gynecological disorder affecting women in their reproductive years. It is reported that patients with endometriosis have reduced implantation and pregnancy rates compared to healthy women. According to the various previous studies, the quality of the…
Key Points Lay SummaryHow to preserve fertility in women with “ovarian endometriosis”?
Although there are many treatment modalities in endometriosis, optimal treatment has not been developed yet. The aim of the treatment is to reduce pain, to preserve and improve fertility and to delay recurrence. Ovarian ischemic and perfusion damage during endometriosis…
Key Points Lay SummaryPolymorphism of IL12B May Help Solve Endometriosis
Zhao et al. recently published a paper titled “A functional promoter polymorphism in interleukin 12B gene is associated with an increased risk of ovarian endometriosis” in Gene. The research group from Hebei Medical University wanted to explore the potential roles…
Key Points Lay SummaryKey to Understanding Ovarian Endometriosis may lay in the Peptides
Xue et al. recently published a paper titled “Peptidomic Analysis of Endometrial Tissue from Patients with Ovarian Endometriosis” in Cellular Physiology and Biochemistry. The research group from various departments of Nanjing Medical University wished to better understand the pathogenesis of…
Key Points Lay SummaryNew Approach could help Preoperative Differentiation of Endometriosis and Cancer
Researchers in Japan identified some radiological parameters that could be used to differentiate between endometriosis-associated ovarian cancer (EAOC) and a particular type of benign ovarian endometriosis (OE), making it easier for doctors to offer the right treatment to women who…
Key Points Lay Summary